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Lacticaseibacillus paracasei 207-27 (also known as LPB27) is a probiotic bacterial strain originally isolated from healthy infant feces. It is being investigated for its immunomodulatory, anti-inflammatory, and neuroendocrine effects. Research suggests it may improve gut microbiota diversity, enhance intestinal barrier function, and modulate the gut-brain axis, potentially impacting sleep quality and stress response. Clinical studies, including those sponsored by BY-HEALTH and West China Second University Hospital, have evaluated its efficacy in managing infantile atopic dermatitis and improving sleep in adults under mild stress.
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