Drug intelligence / Profile preview

lacticaseibacillus paracasei 207-27

Development stage
Unknown
Lead developer
By-Health
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Lacticaseibacillus paracasei 207-27 (also known as LPB27) is a probiotic bacterial strain originally isolated from healthy infant feces. It is being investigated for its immunomodulatory, anti-inflammatory, and neuroendocrine effects. Research suggests it may improve gut microbiota diversity, enhance intestinal barrier function, and modulate the gut-brain axis, potentially impacting sleep quality and stress response. Clinical studies, including those sponsored by BY-HEALTH and West China Second University Hospital, have evaluated its efficacy in managing infantile atopic dermatitis and improving sleep in adults under mild stress.

Brand names
LPB27LPB-27LPB 27
Other names
Lactobacillus paracasei 27Lacticaseibacillus paracasei 207-27LPB27LPB-27LPB 27

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