Drug intelligence / Profile preview

Lactiplantibacillus plantarum IOB602

Development stage: Preclinical
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

*Lactiplantibacillus plantarum* IOB602 (LP602) is a specific probiotic bacterial strain, formerly classified within the *Lactobacillus* genus, that is being investigated for its psychobiotic and postbiotic potential in treating depression. Research indicates that the strain and its derived postbiotics can ameliorate depression-like behaviors by modulating the gut-brain axis. Its mechanism of action involves the regulation of the hypothalamic-pituitary-adrenal (HPA) axis (reducing stress-induced hyperactivity), increasing the levels of monoamine neurotransmitters such as serotonin and norepinephrine in the brain, and promoting a healthy gut microbiota composition that increases the production of short-chain fatty acids (SCFAs). It is currently in the preclinical research stage, primarily focused on mental health and neuroendocrine regulation.

Other names: Lactobacillus plantarum IOB602

Beyond the preview

Go deeper on Lactiplantibacillus plantarum IOB602.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Lactiplantibacillus plantarum IOB602.

Explore the full profile