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Lactiplantibacillus plantarum TWK10
- Development stage
- Unknown
- Lead developer
- Synbio Tech
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactiplantibacillus plantarum TWK10 is a specific strain of probiotic bacteria originally isolated from Taiwanese kimchi. [2, 6, 9] It is developed and manufactured by Synbio Tech Inc. and is investigated for its health benefits, particularly in the areas of sports nutrition, muscle health, obesity, and constipation. [1, 5, 7] Clinical and preclinical studies suggest that TWK10 exerts its effects by modulating the gut microbiome, increasing the production of short-chain fatty acids (SCFAs), downregulating transcription factors related to adipocytes, and regulating gastrointestinal hormones. It has been shown to improve cardiorespiratory endurance, reduce body fat, increase muscle mass, and alleviate constipation. [10] The strain has received a Self-affirmed GRAS (Generally Recognized As Safe) status in the United States and has been approved for health claims related to anti-fatigue in Taiwan. [3, 12] It is available as both a live probiotic and a heat-killed postbiotic, allowing for its use in a variety of dietary supplements and functional foods. [1]
- Brand names
- TWK10®Pro-biotic Premium Performance
- Other names
- Lactobacillus plantarum TWK10
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