lactium

Lactium is a **bioactive decapeptide complex** derived from the hydrolysis of **bovine milk alpha-S1 casein** (milk protein) that contains α-casozepine as its main active component. It is produced via food-grade tryptic hydrolysis and is marketed as a **dietary supplement** for managing stress, anxiety, sleep quality, and stress-related symptoms. Lactium does not possess sedative or addictive effects typical of benzodiazepines and is generally considered safe, with no major side effects reported at recommended dosages. Its **mechanism of action** involves binding to GABA-A receptors at the benzodiazepine site, modulating GABAergic neurotransmission, enhancing relaxation, and reducing stress-induced cortisol levels. It is not a pharmaceutical or prescription medication but a nutraceutical/functional food ingredient. It is used globally in various product formulations and has been tested in multiple clinical studies for stress reduction, sleep disorders, and psychodermatological conditions such as acne vulgaris[1][3][4][6][7].

Brand names

Lactium

Other names

alpha-S1 casein hydrolysatealpha-S-1 casein hydrolysatealpha-S 1 casein hydrolysateα-casozepinemilk protein hydrolysatebovine milk alpha S1 casein hydrolysate