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Lactobacillus acidophilus LA-06

Development stage: Unknown
Lead developer: Weihai Municipal Hospital
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

Lactobacillus acidophilus LA-06 is a specific probiotic strain of the species *Lactobacillus acidophilus* being investigated as a live biotherapeutic product. It is primarily studied for its potential to modulate the gut-thyroid axis, particularly in patients with newly diagnosed Graves' disease. The strain is hypothesized to influence immune function and gut microbiota composition, which may in turn alleviate psychiatric comorbidities such as anxiety, depression, and insomnia often associated with hyperthyroidism. In clinical research, it is typically evaluated as an adjunctive therapy to standard antithyroid medications like methimazole.

Other names: L. acidophilus LA-06

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