Drug intelligence / Profile preview

lactobacillus casei

Development stage
Phase 4
Lead developer
Yakult Honsha
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral, Vaginal, Topical
01

Overview

lactobacillus casei is a probiotic bacterial species used as an orally administered live microbial therapeutic or supplement intended to modulate the intestinal microbiome and host immune-metabolic signaling. Across the provided public sources, it appears in preclinical and clinical contexts for metabolic disease, gastrointestinal inflammation, alcohol-related gut-brain effects, and other inflammatory conditions. Its proposed mechanism is not a single receptor-target interaction; rather, it acts through microbiome modulation, reinforcement of gut barrier function, suppression of pro-inflammatory cytokine signaling, and downstream effects on host metabolism and immune tone. The name is somewhat nonspecific in practice because some studies use unspecified L. casei preparations while others use a defined strain such as Lactobacillus casei strain Shirota, so annotations should be interpreted as applying to the species-level agent rather than a uniquely characterized commercial strain unless explicitly stated.

Other names
Lactobacillus caseiL. casei干酪乳杆菌

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