Drug intelligence / Profile preview

Lactobacillus casei LBC80R

Development stage
Unknown
Lead developer
Kerry
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Lactobacillus casei LBC80R is a proprietary probiotic strain of the species *Lacticaseibacillus casei* (formerly *Lactobacillus casei*) developed by Bio-K+. It is a primary component of the Bio-K+ probiotic product line, which typically features a combination of three strains: L. casei LBC80R, L. rhamnosus CLR2, and L. acidophilus CL1285. The strain is designed to support digestive and immune health by modulating the intestinal microbiota, enhancing the gut barrier function, and competing with pathogens for nutrients and adhesion sites. Clinical studies have demonstrated that the Bio-K+ multi-strain formula is effective in reducing the risk of antibiotic-associated diarrhea (AAD) and Clostridioides difficile infections (CDI) in hospitalized patients. It is commercially available in various oral formats, including fermented dairy and soy beverages as well as enteric-coated capsules.

Brand names
Bio-K+
Other names
L. casei LBC80RLacticaseibacillus casei LBC80RLactobacillus casei LBC80R®

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