lactobacillus crispatus 197 + lactobacillus gasseri CCFM1201

This product is a combination of two probiotic bacterial strains, Lactobacillus crispatus 197 and Lactobacillus gasseri CCFM1201. Both are lactic acid bacteria commonly found in the human microbiota, particularly in the vaginal and gastrointestinal tracts. Lactobacillus crispatus is well-documented for its protective role in maintaining vaginal health by producing lactic acid and hydrogen peroxide, which help maintain an acidic environment that inhibits pathogenic bacteria[1][5]. Certain strains such as M247 have demonstrated high colonization ability of both the gut and vagina when administered orally, resistance to antibiotics like metronidazole, and efficacy in reducing recurrence of bacterial vaginosis, candidiasis, urinary tract infections, and modulating HPV infection status[2]. Lactobacillus gasseri is another beneficial species with similar probiotic properties; it can produce bacteriocins (antimicrobial peptides) that inhibit pathogens. Genomic studies show L. crispatus generally harbors more bacteriocin genes than L. gasseri but both contribute to competitive exclusion of harmful microbes[3]. The combination aims to leverage complementary mechanisms for restoring or maintaining healthy microbiota balance—primarily through competitive exclusion of pathogens via acidification (lactic acid production), hydrogen peroxide generation, proteolytic activity, co-aggregation with other beneficial microbes or pathogens (to prevent pathogen adhesion), and direct antimicrobial effects from bacteriocins[3][5].

Other names

卷曲乳杆菌197 + 格式乳杆菌CCFM1201