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Lactobacillus fermentum + Lactobacillus rhamnosus + Lactobacillus plantarum + Bifidobacterium longum is a multi-strain probiotic combination composed of four specific bacterial strains: *Lactobacillus fermentum* LF16 (DSM 26956), *Lactobacillus rhamnosus* LR06 (DSM 21981), *Lactobacillus plantarum* LP01 (LMG P-21021), and *Bifidobacterium longum* BL04 (DSM 23233). Developed by Activated Probiotics and marketed under the brand name Biotic Mood, this live biotherapeutic product targets the gut-brain axis to improve sleep quality and manage mood disorders. Its mechanism of action involves the modulation of gut microbiota composition and the maintenance of host immune homeostasis, specifically by influencing cytokine balance and neurotransmitter signaling pathways associated with the gut-brain axis. It is typically administered orally in capsule form.
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