Drug intelligence / Profile preview

Lactobacillus gasseri BNR17

Development stage
Unknown
Lead developer
AceBiome
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Lactobacillus gasseri BNR17 is a specific probiotic strain of the species *Lactobacillus gasseri*, originally isolated from human breast milk. It is used as a dietary supplement and live biotherapeutic product, primarily for its potential benefits in metabolic health, including anti-obesity effects and improvement of gut health. Preclinical studies have shown that administration of L. gasseri BNR17 can reduce body weight gain, adipose tissue mass, and serum leptin/insulin levels in animal models by upregulating fatty acid oxidation genes (ACO, CPT1, PPARα, PPARδ) and downregulating fatty acid synthesis genes (SREBP-1c, ACC). Clinical trials in overweight or obese adults have demonstrated reductions in visceral fat area and waist circumference after supplementation with this strain for 12 weeks[2][5][6]. Additionally, randomized controlled trials suggest it may improve symptoms of diarrhea-predominant irritable bowel syndrome (IBS-D), including abdominal pain and stool frequency[8]. The mechanism involves modulation of host metabolism via changes to the gut microbiota composition and enhancement of intestinal barrier function.

Brand names
Acebiome BNR17 Diet Probiotics BNRThin ProDr. Mercola Biothin Probiotic Lactobacillus Gasseri
Other names
L. gasseri BNR17Lactobacillus gasseri strain BNR17

Beyond the preview

Go deeper on Lactobacillus gasseri BNR17.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Lactobacillus gasseri BNR17.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call