Drug intelligence / Profile preview

lactobacillus jensenii LBV116

Development stage
Unknown
Lead developer
Chr. Hansen
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Lactobacillus jensenii LBV116 is a **vaginal-specific probiotic strain** of Lactobacillus jensenii, naturally found in the lower reproductive tract of women and comprising around 25% of a healthy vaginal microbiota[1][2][5]. It is specifically formulated to support and restore vaginal health, particularly by producing bioactive compounds—such as hydrogen peroxide—that help maintain the vagina’s natural defenses and inhibit pathogenic bacteria[1][5]. LBV116 aids in acidification and dominance of lactobacilli in the vaginal ecosystem, which is associated with lower risks of bacterial vaginosis, sexually transmitted infections, pelvic inflammatory disease, and preterm birth[1][2]. The strain is included in several clinically researched multi-strain oral probiotic blends, notably together with L. crispatus LBV88, L. rhamnosus LBV96, and L. gasseri LBV150N[1][2][5]. Clinical studies suggest oral administration can trend toward restoring healthy vaginal microbiota and improving Nugent scores in women with intermediate microbiota[5].

Brand names
Ultimate VUltimate UTJarro-Dophilus Women
Other names
Lactobacillus jensenii LBV116L. jensenii LBV116

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