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lactobacillus paracasei 317
- Development stage
- Unknown
- Lead developer
- University of Tartu
- Modality
- Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactobacillus paracasei 317 is a specific strain of probiotic bacteria that has been investigated for its potential role in biodefense. Developed through research supported by the Estonian Science Foundation and conducted at the University of Tartu, this strain was evaluated in human volunteer studies to determine its safety, persistence in the gastrointestinal tract, and ability to modulate the host's immune response. The mechanism of action relies on the competitive exclusion of pathogens, production of antimicrobial metabolites (such as lactic acid), and stimulation of non-specific mucosal immunity. The primary goal of its development is to provide a biological shield or passive immunity to individuals who may be exposed to bioterrorism agents, enhancing their natural resistance to infection.
- Other names
- L. paracasei 317Lactobacillus paracasei strain 317
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