Drug intelligence / Profile preview

lactobacillus pentosus KCA1

Development stage: Unknown
Lead developer: University of Benin
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral, Topical

Overview

Lactobacillus pentosus KCA1 is a specific probiotic bacterial strain originally isolated from the vaginal microbiota of a healthy premenopausal woman. It is characterized as a live biotherapeutic product with metabolic versatility, capable of producing lactic acid and a cyclic bacteriocin designated as pentocin KCA1. The strain is primarily investigated for its ability to modulate the vaginal and gut microbiomes to treat conditions such as bacterial vaginosis (BV) by lowering local pH and displacing pathogens. Additionally, topical applications of KCA1 have been studied for their ability to reduce axillary malodor by decreasing the relative abundance of odor-producing *Corynebacterium* species and downregulating microbial genes encoding pyridoxal phosphate (PLP)-dependent enzymes involved in the production of volatile thioalcohols.

Other names: Lactobacillus plantarum KCA1

Beyond the preview

Go deeper on lactobacillus pentosus KCA1.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on lactobacillus pentosus KCA1.

Explore the full profile