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Lactobacillus plantarum + Lactobacillus casei + Bifidobacterium breve + galacto-oligosaccharides
- Development stage
- Preclinical
- Lead developer
- Tongji Hospital
- Modality
- Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactobacillus plantarum + Lactobacillus casei + Bifidobacterium breve + galacto-oligosaccharides is a novel synbiotic formulation developed by researchers at Tongji Hospital. It consists of three probiotic strains (Lactobacillus plantarum, Lactobacillus casei, and Bifidobacterium breve) combined with the prebiotic galacto-oligosaccharides (GOS). This synbiotic formulation is designed to prevent calcium oxalate (CaOx) nephrolithiasis (kidney stones) by restoring gut microbiota homeostasis, repairing intestinal barrier integrity, and modulating mucosal oxalate transporter expression, which collectively reduces systemic oxalate overload and prevents renal stone formation.
- Other names
- Lactiplantibacillus plantarum + Lacticaseibacillus casei + Bifidobacterium breve + galacto-oligosaccharidesLactobacillus plantarum + Lactobacillus casei + Bifidobacterium breve + galactooligosaccharidesLp. plantarum + Lc. casei + B. breve + GOSLp. plantarum + Lc. casei + B. breve + GOS synbiotic
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