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Drug intelligence / Profile preview
Lactobacillus plantarum 1008
- Development stage
- Preclinical
- Lead developer
- Synbio Tech
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactobacillus plantarum 1008 (also known as Lactiplantibacillus plantarum 1008 or LP1008) is a Gram-positive probiotic bacterial strain originally isolated from fermented Taiwanese pickled cabbage. Developed by SynbioTech, LP1008 has been investigated for its potential therapeutic benefits in age-related cognitive impairment, skeletal muscle atrophy, and obesity-induced male reproductive dysfunction (hypogonadism). Preclinical studies demonstrate that LP1008 supplementation can improve blood cholesterol, insulin resistance, and hepatic function, while enhancing testicular antioxidant capacity, restoring testosterone biosynthesis, and improving sperm quality. It acts by modulating the gut microbiota, reducing systemic inflammation, and suppressing oxidative stress, apoptosis, and autophagy in target tissues.
- Other names
- L. plantarum 1008Lactiplantibacillus plantarum 1008
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