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*Lactobacillus plantarum* A87 is a specific probiotic bacterial strain belonging to the species *Lactiplantibacillus plantarum* (formerly *Lactobacillus plantarum*). It is primarily developed and investigated for its metabolic health benefits, particularly in the management of obesity and related metabolic disorders. The strain exerts its therapeutic effects through the modulation of the gut microbiota and the regulation of host lipid metabolism. Research indicates that A87 can suppress the expression of key adipogenic transcription factors, including peroxisome proliferator-activated receptor gamma (PPAR-gamma) and CCAAT/enhancer-binding protein alpha (C/EBP-alpha), thereby inhibiting adipocyte differentiation and fat accumulation. Additionally, it has been observed to reduce systemic inflammation and improve glucose tolerance in preclinical models and human clinical trials. It is typically commercialized as a functional food ingredient or a dietary supplement for weight management.
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