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Drug intelligence / Profile preview
Lactobacillus plantarum DR7
- Development stage
- Unknown
- Lead developer
- AB-BIOTICS
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
AB-DR7 is a specific probiotic strain of *Lactobacillus plantarum* developed by AB-BIOTICS. It is primarily targeted at improving respiratory health and supporting the immune system, specifically by reducing the duration and frequency of upper respiratory tract infections (URTIs). The strain works by modulating the gut-lung axis, enhancing the production of anti-inflammatory cytokines such as IL-10, and reducing pro-inflammatory markers like TNF-α and IFN-γ. Clinical studies have also suggested benefits in the gut-brain axis, including stress and anxiety reduction through the modulation of serotonin pathways and cortisol levels.
- Other names
- L. plantarum DR7
02
Targets
IFNG (Interferon gamma)IL10 (Interleukin-10)TNFA (Tumor necrosis factor alpha (soluble))
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