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Lactobacillus plantarum DR7
- Development stage
- Unknown
- Lead developer
- AB-BIOTICS
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
AB-DR7 is a specific probiotic strain of *Lactobacillus plantarum* developed by AB-BIOTICS. It is primarily targeted at improving respiratory health and supporting the immune system, specifically by reducing the duration and frequency of upper respiratory tract infections (URTIs). The strain works by modulating the gut-lung axis, enhancing the production of anti-inflammatory cytokines such as IL-10, and reducing pro-inflammatory markers like TNF-α and IFN-γ. Clinical studies have also suggested benefits in the gut-brain axis, including stress and anxiety reduction through the modulation of serotonin pathways and cortisol levels.
- Other names
- L. plantarum DR7
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))IL10 (Interleukin-10)IFNG (Interferon gamma)
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