Drug intelligence / Profile preview

lactobacillus plantarum KABP-51

Development stage
Unknown
Lead developer
AB-BIOTICS
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral (as Probiotic Supplement Or As Ingredient In Functional Foods/beverages)[1]
01

Overview

**Lactobacillus plantarum KABP-51** (also listed as *Lactiplantibacillus plantarum* KABP051) is a specific probiotic strain isolated from human feces and cow’s milk and extensively characterized for use as a **live biotherapeutic product**, particularly as a supplement in functional foods and beverages[1]. It is known for its high environmental resilience, metabolic versatility, and ability to survive and proliferate in diverse conditions such as fruit juices. Its mechanism includes fermentation of plant-derived substrates, malolactic fermentation, and production of various bioactive compounds—among them phenyllactic acid (antimicrobial), N-acetyl glutamine (immunomodulatory and anti-fatigue), nicotinic acid (vitamin B3), and acetylcholine (neurotransmitter)[1]. Clinical trials have explored its effects on body composition, gut microbiome modulation, and mood in healthy overweight adults[3]. Its primary indications are as a probiotic for supporting gut health, modulating metabolic profiles, enhancing antioxidant capacity, and potentially affecting lipid profiles and immune modulation. Developer information is not explicitly provided, but related clinical studies and probiotic product development may involve academic or commercial entities specializing in microbiome and probiotic research.

Brand names
DR7DR-7DR 7DR7™AB-DR7AB-DR-7AB-DR 7INNERIM
Other names
lactiplantibacillus plantarum KABP051L. plantarum KABP051
02

Targets

BSH (Bile salt hydrolase)

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