Drug intelligence / Profile preview

Lactobacillus plantarum LPL28 metabolites

Development stage
Preclinical
Lead developer
Synbio Tech
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Lactobacillus plantarum LPL28 metabolites are a collection of bioactive compounds, often referred to as postbiotics, produced by the specific probiotic bacterial strain Lactobacillus plantarum LPL28. These metabolites have demonstrated a range of biological activities, including selective cytotoxicity against cancer cells, inhibition of autophagy-related responses, modulation of gut microbiota composition, and improvement of metabolic functions. They also contribute to immune system modulation by influencing cytokine levels and enhancing gut barrier integrity. Furthermore, these metabolites have shown potential in alleviating allergic reactions. Research suggests their utility in both food compositions and potential pharmaceutical applications.

Other names
L. plantarum LPL28 metabolitespostbiotic metabolites of Lactobacillus plantarum LPL28
02

Targets

Neuraminidase

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