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Lactobacillus plantarum PL15A
- Development stage
- Preclinical
- Lead developer
- Thankcome Biotechnology
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactobacillus plantarum PL15A, also classified as Lactiplantibacillus plantarum PL15A, is a specific strain of probiotic bacteria. [3, 5] It is supplied by the Chinese company Thankcome Bio (Suzhou) Co., Ltd. [4, 8] This strain is used as an ingredient in multi-strain commercial products, including yogurt starters and dietary supplements intended for functions like weight management and immune system regulation. [1, 6, 13] Additionally, L. plantarum PL15A has been utilized in research for fermenting traditional medicinal plants, such as Gastrodia elata. [4, 11] Studies in animal models suggest that this fermentation process may help alleviate cognitive deficits associated with Alzheimer's disease by modulating gut microbiota and neurotransmitter levels. [4, 11] Like other probiotics, its general mechanism involves promoting a healthy balance of intestinal flora, which can influence the host's health through the gut-brain axis. [11]
- Other names
- 植物乳杆菌PL15ALactiplantibacillus plantarum PL15A
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