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Lactobacillus plantarum TCI507
- Development stage
- Unknown
- Lead developer
- TCI
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactobacillus plantarum TCI507 is a probiotic strain extracted from orange peels. It has been shown to have multiple health benefits including weight loss effects and cholesterol-lowering properties. The strain works as a microbiome modulator and has been verified through in vitro experiments to hydrolyze bile salts and inhibit fat cell production. Clinical studies have demonstrated that TCI507 can effectively reduce total cholesterol and low-density lipoprotein levels in human blood, promoting cardiovascular health. The strain was deposited at the Food Industry Development Research Institute on December 21, 2006, with the deposit number BCRC910806.
- Other names
- Lactobacillus plantarum TCI507BCRC910806BCRC-910806BCRC 910806
02
Targets
LDLR (Low-density lipoprotein receptor)APOA1 (Apolipoprotein A-I)SCARB1 (Scavenger receptor class B member 1)
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