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lactobacillus plantarum TCI999

Development stage: Preclinical
Lead developer: TCI
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

Lactobacillus plantarum TCI999 (also referred to as Lactiplantibacillus plantarum TCI999) is a specific probiotic strain developed by the Taiwanese biotechnology company TCI Co., Ltd. It is primarily investigated for its potential to promote hair growth and improve scalp health through the modulation of the gut-skin axis. Clinical evidence, including a double-blind, placebo-controlled trial, suggests that oral supplementation with TCI999 can influence the gut microbiome composition, which in turn may regulate systemic inflammation and nutrient pathways essential for hair follicle maintenance and growth. As a live biotherapeutic product, it represents a non-invasive approach to managing hair density and related dermatological conditions.

Other names: Lactiplantibacillus plantarum TCI999

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