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Lactobacillus probiotic supplement
- Development stage
- Unknown
- Lead developer
- Beni-Suef University
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactobacillus probiotic supplement (Beni-Suef University) is a microbial therapy being evaluated in a Phase 3 clinical trial for the management of knee osteoarthritis. Developed by researchers at Beni-Suef University, this intervention involves the oral administration of a Lactobacillus-based probiotic formula twice daily as an adjunct to standard care. The therapeutic approach leverages the gut-joint axis, where the modulation of gut microbiota is intended to reduce systemic pro-inflammatory markers and metabolic endotoxemia, potentially alleviating joint pain, stiffness, and improving physical function in patients with osteoarthritis.
- Other names
- Probiotic FormulaLactobacillus
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