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lactobacillus reuteri
- Development stage
- Phase 4
- Lead developer
- Shenzhen People's Hospital
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Topical
01
Overview
*Lactobacillus reuteri* is a probiotic bacterium being investigated as a topical live biotherapeutic product for the treatment of androgenetic alopecia (AGA). Developed by researchers at Shenzhen People's Hospital, this microbiome-targeting approach is based on the concept that restoring balance to the scalp's microbial community can support hair follicle function and mitigate hair loss. The treatment involves the daily topical application of a solution containing approximately 10^9 colony-forming units (CFU) of *L. reuteri*. It is hypothesized that the probiotic modulates the local scalp environment, potentially reducing inflammation or influencing the hormonal pathways that lead to follicle miniaturization, thereby providing a novel alternative or complement to standard treatments like minoxidil.
- Brand names
- BioGaia
- Other names
- L. reuteriLactobacillus reuteri probiotic solution
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