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This product is a **combination synbiotic** comprised of the probiotic bacterium *Lactobacillus reuteri* (also sometimes referred to as *Limosilactobacillus reuteri*) and the prebiotic **galacto-oligosaccharides (GOS)**. *L. reuteri* is a Gram-positive, rod-shaped bacterium naturally present in the gastrointestinal tracts of humans and animals and used as a probiotic for its health benefits. GOS are non-digestible carbohydrates that serve as selective fermentation substrates and promote the growth and metabolic activity of beneficial gut microbes, particularly lactobacilli and bifidobacteria. In this combination, GOS supports the colonization and persistence of *L. reuteri* by providing it with a preferential carbon and energy source. This synbiotic approach may help improve gut health by enhancing barrier function, reducing intestinal inflammation (by inhibition of NF-κB activation), boosting short-chain fatty acid (SCFA) production, and increasing osteoblastogenesis and bone mineralization. Preconditioning *L. reuteri* with GOS can further enhance the metabolic and colonization advantages. Primary indications under investigation or use include **intestinal inflammation (such as ulcerative colitis)**, enhancement of gut barrier function, and potentially prevention of age-related bone loss and improvement in bone strength[1][3][4].
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