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Lactobacillus reuteri ATCC PTA 5289 is a probiotic bacterial strain developed and marketed by BioGaia AB. As a live biotherapeutic agent, it is primarily utilized in consumer health products targeting oral health, gut health, and immune support. The strain's mechanism of action involves the modulation of the local microbiota and the host's immune response. Specifically, it helps maintain a healthy balance in the oral cavity by displacing pathogenic bacteria and influencing inflammatory pathways. In clinical applications, it is frequently used in combination with another strain, L. reuteri DSM 17938, to treat conditions such as gingivitis, periodontitis, and oral mucositis. It is typically administered orally in the form of lozenges, tablets, or drops.
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