Drug intelligence / Profile preview

lactobacillus rhamnosus

Development stage
Phase 4
Lead developer
Junlebao Dairy
Modality
Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Lactobacillus rhamnosus is a species of probiotic bacteria commonly used as a dietary supplement. It is known for its ability to modulate the gut microbiota and immune system. Studies have investigated its potential therapeutic effects across various conditions, including improving oral flora, managing metformin-induced diarrhea, preventing bacterial and viral infections in infants, and influencing immune responses in conditions like systemic lupus erythematosus and atopic dermatitis. It has also been studied for its role in polycystic ovary syndrome, obesity, psoriasis, Helicobacter pylori eradication, constipation, and periodontitis.

Brand names
Lcr Restituo
Other names
Lactobacillus casei rhamnosusLacticaseibacillus rhamnosusL. rhamnosusLactobacillus casei subsp. rhamnosus
02

Targets

FOXP3 (Forkhead box protein P3)IL10 (Interleukin-10)IL-2 (Interleukin 2)IL-6 (Interleukin 6)TGFB (GARP–latent transforming growth factor beta 1 complex)

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