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lactobacillus rhamnosus CCFM1131
- Development stage
- Preclinical
- Lead developer
- Jiangnan University
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactobacillus rhamnosus CCFM1131 is a specific probiotic strain of the species Lactobacillus rhamnosus, a lactic acid bacterium commonly found in the human gut and used as a dietary supplement. This particular strain has demonstrated potential for reducing serum uric acid levels and alleviating hyperuricemia, likely through inhibition of xanthine oxidase activity in serum and liver. As with other L. rhamnosus strains, it is considered to have beneficial effects on gut microbiota modulation and may offer additional health benefits related to metabolic regulation[10].
02
Targets
XO (Xanthine Oxidoreductase)
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