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lactobacillus rhamnosus LR607
- Development stage
- Phase 2
- Lead developer
- H&H Group
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
*Lactobacillus rhamnosus* LR607 is a specific probiotic strain belonging to the *Lactobacillaceae* family, extensively utilized in the development of pediatric nutritional supplements and live biotherapeutic products. Developed by the H&H Group (Biostime), LR607 is characterized by its ability to survive transit through the gastrointestinal tract and adhere to intestinal epithelial cells. Its mechanism of action involves the modulation of the host's innate and adaptive immune responses, enhancement of the intestinal mucosal barrier, and competitive exclusion of enteric pathogens. Clinical investigations have primarily focused on its role in reducing the frequency and severity of common respiratory tract infections (RTIs) and gastrointestinal distress in infants and young children. By influencing the composition and metabolic activity of the gut microbiota, LR607 promotes a balanced microbial environment conducive to overall health and immune resilience.
- Brand names
- Biostime
- Other names
- Lacticaseibacillus rhamnosus LR607L. rhamnosus LR607
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