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Lactobacillus rhamnosus probiotic yogurt
- Development stage
- Unknown
- Lead developer
- Centro Pediatrico Albina de Patino
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
This is a probiotic yogurt preparation containing the bacterium *Lactobacillus rhamnosus* (10^8 CFU/mL), specifically developed by the Centro Pediatrico Albina de Patino in Cochabamba, Bolivia. It was designed as a cost-effective alternative to lyophilized probiotic products for managing acute watery diarrhea in pediatric populations. The intervention functions as a live biotherapeutic, aiming to restore intestinal microflora balance and potentially enhance mucosal immune responses to combat enteric pathogens. In a randomized, double-blind, controlled clinical trial involving children aged 10 to 35 months, the preparation demonstrated therapeutic efficacy comparable to the standard probiotic *Saccharomyces boulardii* in reducing the duration and severity of diarrheal episodes.
- Other names
- Probiotic yogurtLactobacillus rhamnosus yogurt
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