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Lactobacillus rhamnosus R7970 is a specific probiotic bacterial strain belonging to the species *Lactobacillus rhamnosus* (also known as *Lacticaseibacillus rhamnosus*). This strain has demonstrated several beneficial effects in clinical and preclinical studies. It is notable for its ability to modulate intestinal microbiota, enhance digestive function, and improve immune responses. Mechanistically, it acts by inhibiting pathogenic bacteria (including both bacteria and fungi), reducing inflammation in the gut, and supporting mucosal barrier integrity. Key applications of Lactobacillus rhamnosus R7970 include: - Prevention and relief of gastrointestinal discomfort following mechanical injury such as colonoscopy (reducing symptoms like abdominal pain, diarrhea, bloating, indigestion, and rectal bleeding)[3]. - Prevention or treatment of infectious diseases caused by pathogenic bacteria or fungi—including oral pathogens—due to its broad-spectrum antimicrobial activity[6]. - Potential prevention of inflammatory bowel disease (IBD) through anti-inflammatory effects on the gut[4]. The strain is recognized for its safety profile; it does not exhibit hemolytic activity in standard tests[6] and shows sensitivity to most antibiotics except vancomycin. It can be used alone or combined with vancomycin for enhanced infection control.
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