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lactobacillus rhamnosus x253
- Development stage
- Preclinical
- Lead developer
- Junlebao Dairy
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Lactobacillus rhamnosus X253 is a specific probiotic bacterial strain investigated for its potential benefits in oral and gastrointestinal health. In clinical studies, such as NCT05123651, it has been formulated as a lozenge to evaluate its impact on oral flora, dental caries, oral odor, and gum bleeding. The strain is characterized by its ability to colonize the oral cavity and modulate the local microbiome, potentially inhibiting the growth of cariogenic pathogens. It has also been studied for its effects on defecation frequency, suggesting broader probiotic applications.
- Other names
- L. rhamnosus X253Lactobacillus rhamnosus strain X253
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