Drug intelligence / Profile preview

lactobacillus vaginal capsules

Development stage
Unknown
Lead developer
Sichuan Yanyang Biotechnology
Modality
Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Vaginal
01

Overview

Lactobacillus vaginal capsules are a live biotherapeutic product containing probiotic bacteria, most commonly *Lactobacillus delbrueckii* or *Lactobacillus acidophilus*. These capsules are administered intravaginally to restore and maintain a healthy vaginal microbiome, which is essential for preventing and treating urogenital infections. The mechanism of action involves the colonization of the vaginal mucosa by Lactobacilli, which produce lactic acid to maintain an acidic environment (pH < 4.5), hydrogen peroxide to inhibit anaerobic bacteria, and bacteriocins that directly target pathogens. In clinical practice, they are frequently used as an adjunct to standard antibiotics (like metronidazole) or antifungals (like fluconazole) to treat bacterial vaginosis and vulvovaginal candidiasis, reducing recurrence rates by re-establishing the protective microbial barrier. Recent research also explores their efficacy in promoting the clearance of high-risk human papillomavirus (HPV) infections by modulating local immune responses and microbial balance.

Brand names
Duo Mei An
Other names
Living Preparation of Lactobacillus vaginal capsulesLactobacillus delbrueckii vaginal capsulesLactobacillus acidophilus vaginal capsulesLactobacillus Vaginal Capsules (Living)

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