Drug intelligence / Profile preview

lactobacillus vaginalis

Development stage
Phase 2
Lead developer
Jiangsu Provincial People's Hospital
Modality
Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration
Vaginal
01

Overview

Lactobacillus vaginalis refers to a live biotherapeutic preparation, typically administered as vaginal capsules, containing viable *Lactobacillus* species intended to restore or maintain a healthy vaginal microbiota. In the context of clinical research conducted by Shanghai General Hospital, it is being investigated as an adjuvant therapy alongside dydrogesterone and metformin for the treatment of endometrial hyperplasia (EH). The rationale for this intervention is based on the hypothesis that the vaginal and uterine microbiota influence endometrial health and that restoring a *Lactobacillus*-dominant environment may improve the complete remission (CR) rate of the endometrium by modulating local inflammation or metabolic pathways. While the name is used in clinical trial registries, it likely refers to a generic or specific probiotic product containing common vaginal species such as *L. crispatus* or *L. acidophilus* rather than a single taxonomically distinct species named *L. vaginalis*.

Other names
vaginal lactobacillusvaginal lactobacillus viable capsules

Beyond the preview

Go deeper on lactobacillus vaginalis.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on lactobacillus vaginalis.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call