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Drug intelligence / Profile preview
lactoferrin
- Development stage
- Phase 4
- Lead developer
- Morinaga Milk Industry
- Modality
- Recombinant Proteins and Enzymes
- Administration
- Oral, Intravenous, Intranasal, Topical, Ophthalmic
01
Overview
**Lactoferrin** is a multifunctional iron-binding glycoprotein naturally present in human and bovine milk, especially colostrum. It binds ferric iron and microbial lipopolysaccharide, contributing to antimicrobial, anti-inflammatory, antioxidant, and immunomodulatory activity. The unqualified name is broad and may refer to human, bovine, or recombinant human preparations and to nutraceutical, functional-food, or investigational therapeutic products. Oral bovine lactoferrin has been studied for visceral obesity and prevention of late-onset sepsis in preterm infants, while recombinant human lactoferrin has been evaluated experimentally as an immunomodulatory anticancer therapy.
- Brand names
- efferaLacromin
- Other names
- lactotransferrinLTFLF乳铁蛋白
02
Targets
CD14 (Monocyte differentiation antigen CD14)CXCR4 (C-X-C motif chemokine receptor 4)ITLN1 (Intelectin-1)LSR (Lipolysis-stimulated lipoprotein receptor)
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