Drug intelligence / Profile preview

lactoferrin

Development stage
Phase 4
Lead developer
Morinaga Milk Industry
Modality
Recombinant Proteins and Enzymes
Administration
Oral, Intravenous, Intranasal, Topical, Ophthalmic
01

Overview

**Lactoferrin** is a multifunctional iron-binding glycoprotein naturally present in human and bovine milk, especially colostrum. It binds ferric iron and microbial lipopolysaccharide, contributing to antimicrobial, anti-inflammatory, antioxidant, and immunomodulatory activity. The unqualified name is broad and may refer to human, bovine, or recombinant human preparations and to nutraceutical, functional-food, or investigational therapeutic products. Oral bovine lactoferrin has been studied for visceral obesity and prevention of late-onset sepsis in preterm infants, while recombinant human lactoferrin has been evaluated experimentally as an immunomodulatory anticancer therapy.

Brand names
efferaLacromin
Other names
lactotransferrinLTFLF乳铁蛋白
02

Targets

LSR (Lipolysis-stimulated lipoprotein receptor)CXCR4 (C-X-C motif chemokine receptor 4)ITLN1 (Intelectin-1)CD14 (Monocyte differentiation antigen CD14)

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