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LACTYFERRIN Forte + ZINC Defense
- Development stage
- Discontinued
- Lead developer
- Sesderma
- Modality
- Small Molecules, Recombinant Proteins and Enzymes, Nanoparticles → Drug Delivery Systems
- Administration
- Oral
01
Overview
LACTYFERRIN Forte + ZINC Defense is a combination therapy consisting of liposomal bovine lactoferrin and liposomal zinc, developed by Sesderma Laboratories and investigated by Jose David Suarez, MD. Bovine lactoferrin is a multifunctional glycoprotein that acts as an ACE2 receptor blocker, potentially preventing the SARS-CoV-2 spike protein from binding to and entering host cells. The zinc component is intended to provide additional antiviral and immune-supportive effects. Both components are encapsulated in 100 nm nanoliposomes (phosphatidylcholine) to enhance bioavailability and stability. The combination was evaluated in a Phase 2 clinical trial for the treatment of non-hospitalized patients with mild to moderate COVID-19.
- Brand names
- Sesderma LACTYFERRIN ForteSesderma ZINC Defense
- Other names
- Sesderma LACTYFERRIN Forte and Sesderma ZINC DefenseLiposomal Bovine Lactoferrin and Liposomal ZincLbLf + LZn
02
Targets
Fe2+ (Ferrous iron)ACE2 (Angiotensin-converting enzyme 2)SARS-CoV-2 spike
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