LAG-3 PROTAC-1

LAG-3 PROTAC-1: sourced facts only. name: "Western blot analysis in Raji-LAG3 cells demonstrated that LAG-3 PROTAC-1 and LAG-3 PROTAC-3 induce potent, dose-dependent degradation of LAG-3, with DC50 values of 0.27 μM and 0.42 μM, respectively." [PMID:41052608]; target: "Western blot analysis in Raji-LAG3 cells demonstrated that LAG-3 PROTAC-1 and LAG-3 PROTAC-3 induce potent, dose-dependent degradation of LAG-3, with DC50 values of 0.27 μM and 0.42 μM, respectively." [PMID:41052608]; developer: "Department of Radiology, Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, NY 10065, USA." [PMID:41052608]; modality: "Here, we report the design and validation of the first-in-class PROTACs for targeted degradation of LAG-3." [PMID:41052608]