Laif

Laif is a branded herbal medicinal product containing standardized dry extract of Hypericum perforatum (St. John’s wort), used primarily for the treatment of mild to moderate depressive episodes and, in some formulations, associated anxiety symptoms. It acts as a multi‑target central nervous system modulator: key constituents such as hyperforin and hypericin are thought to inhibit the reuptake of monoamines including serotonin, norepinephrine, and dopamine, modulate glutamatergic and GABAergic neurotransmission, and influence neuroendocrine and neuroinflammatory pathways. Laif is marketed in various oral formulations (typically film‑coated tablets) and is regulated as a phytopharmaceutical, with documented potential for clinically relevant cytochrome P450 and P‑glycoprotein induction leading to numerous drug–drug interactions.

Brand names

Laif