Laif 900

Laif 900 is a herbal medicinal product containing St. John's wort dry extract, primarily used for treating mild to moderate depressive episodes. Each film-coated tablet contains 900 mg of St. John's wort dry extract, which corresponds to approximately 4 g of St. John's wort herb. ## Mechanism of Action Laif 900 works by re-establishing the balance of neurotransmitters in the brain that are responsible for mood, drive, and sleep regulation[1][5]. Depression is often associated with an imbalance of these neurotransmitters, and St. John's wort helps regulate them, particularly those involved in mood regulation[5]. Additionally, it normalizes the increased distribution of the stress hormone cortisol that occurs with excessive stress[5]. ## Usage and Dosage The recommended dosage is one film-coated tablet per day, taken in the morning after breakfast[1][2]. Unlike pain medications, Laif 900 does not work immediately but requires time to build up its full effect. Patients typically experience noticeable improvement within 4 weeks[1]. For optimal results, it's recommended to continue taking the medication for several weeks, even after symptoms have subsided[5]. ## Benefits - Promotes balance of body and soul - Helps with lack of drive, inner unrest, and mental sleep disorders - Has a mood-lifting and balancing effect - Easy intake: only once daily - Non-habit forming and doesn't cause daytime drowsiness[5] ## Safety Profile The clinical safety data indicates that the frequency and severity of adverse effects are lower than those of standard antidepressants[3]. However, there are important safety considerations, particularly regarding drug interactions. Laif 900 interacts with medications metabolized by liver enzymes (CYP3A4, CYP2C9, CYP2C19) and P-glycoprotein[3]. ## Contraindications Laif 900 should not be used concurrently with: - Immunosuppressants (ciclosporin, tacrolimus, sirolimus) - HIV medications (indinavir, nevirapin) - Certain cancer medications (imatinib, irinotecan) - In cases of known allergy to St. John's wort or any other ingredients[6] ## Special Considerations - Not recommended during pregnancy and breastfeeding without medical consultation - Not recommended for children under 12 years - May cause increased photosensitivity (sunburn-like reactions when exposed to strong sunlight)[2] - Should be used under medical supervision if symptoms persist beyond 4 weeks[2] Laif 900 is a prescription medication in some countries due to its potential for interactions with other medications[3]. It's suitable for vegans and is free of gluten and lactose[7].

Brand names

Laif 900Laif900Laif-900