Drug intelligence / Profile preview

lamivudine + abacavir + amprenavir + indinavir

Development stage
Unknown
Lead developer
GSK
Modality
Small Molecules
Administration
Oral
01

Overview

A four-drug combination of **lamivudine**, **abacavir**, **amprenavir**, and **indinavir**, each of which is an antiretroviral used in the treatment of HIV infection. - **Lamivudine** and **abacavir** are nucleoside reverse transcriptase inhibitors (NRTIs) that inhibit the activity of HIV reverse transcriptase, thereby preventing viral replication[1][5]. - **Amprenavir** and **indinavir** are protease inhibitors, which block the HIV protease enzyme necessary for the maturation of infectious viral particles. - This combination targets two steps in the HIV lifecycle (reverse transcription and protease-mediated maturation), intended to reduce viral load and delay resistance. - No single fixed-dose, co-formulated branded product containing this exact four-drug combination is marketed. - Studied in clinical trials as a regimen for HIV-1 infection, but not widely used or marketed as a fixed combination tablet.

02

Targets

Human immunodeficiency virus type 1 reverse transcriptasePR (Progesterone receptor)

Beyond the preview

Go deeper on lamivudine + abacavir + amprenavir + indinavir.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on lamivudine + abacavir + amprenavir + indinavir.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call