Drug intelligence / Profile preview

Landcold Gold

Development stage
Phase 3
Lead developer
Lancet
Modality
Small Molecules
Administration
Oral
01

Overview

Landcold Gold is an oral combination pharmaceutical product developed and marketed by Lancet Pharmaceuticals, a Kolkata-based branded generic company. It is formulated for the symptomatic relief of the common cold, influenza, and allergic rhinitis. The medication typically contains a combination of three active ingredients: paracetamol (acetaminophen), phenylephrine hydrochloride, and chlorpheniramine maleate. Paracetamol serves as an analgesic and antipyretic by inhibiting prostaglandin synthesis in the central nervous system. Phenylephrine acts as a sympathomimetic decongestant by targeting alpha-1 adrenergic receptors to induce vasoconstriction in the nasal passages. Chlorpheniramine maleate is a first-generation H1 receptor antagonist that alleviates allergic symptoms such as sneezing, rhinorrhea, and watery eyes. This combination is a standard therapeutic approach in the Indian generic market for multi-symptom cold relief.

Brand names
Landcold Gold
Other names
Landcold Gold Tablets
02

Targets

Hb (Hemoglobin)PTGES3PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NET (Norepinephrine Transporter)SERT (Sodium-dependent serotonin transporter)TRPV1 (Transient receptor potential cation channel subfamily V member 1)ADRA1A (α1A)ADRA1B (α1B)ADRA1D (α1D)HRH1 (Histamine H1 Receptor)DAT (Dopamine plasma membrane transport protein)KCNH2 (Voltage-gated potassium channel subfamily H member 2)

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