Drug intelligence / Profile preview

lansoprazole sulfone

Development stage
Unknown
Modality
Small Molecules
01

Overview

Lansoprazole sulfone is a small molecule and an oxidative metabolite of the proton pump inhibitor (PPI) lansoprazole. It is considered an experimental compound and is not approved for clinical use as a therapeutic agent. Lansoprazole sulfone has been identified as a human metabolite of lansoprazole and may be referred to in pharmaceutical research as an impurity or related substance during drug synthesis or metabolism studies. Its mechanism of action would be expected to mirror that of its parent compound by inhibiting the hydrogen/potassium-stimulated ATPase (proton pump) in gastric parietal cells; however, there are no established indications or clinical uses for this specific metabolite[1][3].

Other names
lansoprazole sulphone1h-benzimidazole, 2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfonyl)-lansoprazole impurity blansoprazole related compound a
02

Targets

ATP4A (Potassium–transporting ATPase alpha chain 1)

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