Drug intelligence / Profile preview

Lapa-604

Development stage
Preclinical
Lead developer
Southeast University
01

Overview

Lapa-604: sourced facts only. name: "Research has found that Lapa-604 can potently inhibit the proliferation of the tested cancer cells and reverse multiple cancer cell resistance by targeting the EGFR protein and causing severe DNA damage." [PMID:40170467]; target: "Research has found that Lapa-604 can potently inhibit the proliferation of the tested cancer cells and reverse multiple cancer cell resistance by targeting the EGFR protein and causing severe DNA damage." [PMID:40170467]; developer: "Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China." [PMID:40170467]; stage: "More importantly, Lapa-604 presented higher tumor growth inhibitory efficacy than Lapatinib, Cisplatin, or their physical mixtures in both MDA-MB-231 and BT474 xenograft tumor models." [PMID:40170467]

02

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