Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
latanoprost + diclofenac + dorzolamide
- Development stage
- Unknown
- Lead developer
- Aarhus University
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
This drug is a combination therapy consisting of latanoprost, diclofenac, and dorzolamide, investigated by the University of Aarhus for the treatment of diabetic retinopathy. Latanoprost is a prostaglandin F2-alpha analog that typically reduces intraocular pressure; diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis; and dorzolamide is a carbonic anhydrase inhibitor. The combination was studied in the XAVOT trial to determine its effects on retinal vessel diameter and blood flow disturbances in patients with diabetic retinopathy, exploring whether these pharmacological agents can improve retinal hemodynamics.
- Other names
- Latanoprost, diclofenac and dorzolamide (eyedrops)
02
Targets
CA2 (Carbonic Anhydrase 2)PTGFR (Prostaglandin F2 alpha receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
Beyond the preview
Go deeper on latanoprost + diclofenac + dorzolamide.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on latanoprost + diclofenac + dorzolamide.