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LAUR-004 is a preclinical **V-Smart nanomedicine** candidate from Lauren Sciences for **chronic pain**. The product is described as a **nanoparticle-based peptide therapeutic** that packages an **enkephalin payload** for delivery across the central nervous system, with the company indicating targeting of the **entire CNS**. Its intended pharmacology is analgesia through delivery of enkephalin, an endogenous opioid peptide, leading to activation of opioid receptors after CNS distribution. Lauren Sciences has indicated preclinical efficacy with both **intravenous** and **oral** administration using its proprietary V-Smart platform.
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