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LAUR-008
- Development stage
- Unknown
- Lead developer
- Lauren Sciences
- Modality
- Nanoparticles → Drug Delivery Systems, Antibody-Based Therapeutics
- Administration
- Intravenous, Parenteral
01
Overview
LAUR-008 is a non-therapeutic, preclinical-stage proof-of-concept formulation developed by Lauren Sciences using its proprietary V-Smart® nanomedicine platform. It consists of V-Smart® nanovesicles (fabricated from synthetic bolaamphiphiles) encapsulating human immunoglobulin G (hIgG) antibody as a surrogate agent. LAUR-008 is designed to evaluate the platform's ability to non-invasively deliver large biological molecules, specifically antibodies, across the blood-brain barrier (BBB) into the brain via systemic administration. In preclinical studies, systemic administration of LAUR-008 demonstrated significantly higher brain delivery of hIgG compared to free hIgG, proving the platform's potential for CNS-targeted therapeutic delivery.
- Other names
- V-Smart-Human IgG AntibodyV-Smart-hIgGV-Smart-hIgG Antibody
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