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LAUR-301 is a preclinical **nanomedicine** drug candidate from **Lauren Sciences** for **amyotrophic lateral sclerosis** and **motor neuron disease**. It uses the company's **V-Smart** nanoparticle platform to systemically deliver **glial cell-derived neurotrophic factor** after **intravenous** administration, with the stated goal of crossing the blood-brain barrier, targeting deteriorating motor neurons in the brain and spinal cord, and releasing a neuroprotective GDNF payload at sites of degeneration. The program is intended as a disease-modifying neurotrophic therapy designed to protect vulnerable motor neurons and potentially promote neuro-restorative effects in ALS.
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