Drug intelligence / Profile preview

lauryl alcohol diphosphonic acid

Development stage
Unknown
Modality
Small Molecules
Administration
Topical
01

Overview

Lauryl alcohol diphosphonic acid is a synthetic small molecule belonging to the bisphosphonate class of compounds. It contains two phosphonate groups attached to a lauryl (dodecyl) chain. Bisphosphonates are known for their ability to inhibit bone resorption by targeting enzymes involved in the mevalonate pathway. Specifically, lauryl alcohol diphosphonic acid acts as an inhibitor of farnesyl pyrophosphate synthase, an enzyme critical for osteoclast function and survival. This compound has not been approved for medical use and is primarily considered experimental; it has no reported clinical indications or approvals as a pharmaceutical agent[2]. It may also be used as an emulsion stabilizer in cosmetic formulations[5].

Other names
Tensan AO(1-hydroxy-1-phosphonododecyl)phosphonic acid(1-hydroxydodecane-1,1-diyl)diphosphonic acidPhosphonic acid, (1-hydroxydodecylidene)bis-Phosphonic acid,(1-hydroxydodecylidene)di-Phosphonic acid, P,P'-(1-hydroxydodecylidene)bis-
02

Targets

FDPS (Farnesyl pyrophosphate synthase)

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