lavendustin b

Lavendustin b is a synthetic small molecule that acts as a weak tyrosine kinase inhibitor and has been primarily used as a negative control analogue for lavendustin A in biochemical studies. It also functions as an inhibitor of HIV-1 integrase (IN) interaction with its cellular cofactor lens epithelium-derived growth factor (LEDGF/p75), and is reported to be a competitive inhibitor of glucose transporter 1 (GLUT1). Lavendustin b has been studied mainly in research settings rather than clinical development or therapeutic use[1][3][4][5][7]. Its mechanism involves weak inhibition of tyrosine kinases and interference with protein-protein interactions relevant to HIV replication.

Other names

5-[bis[(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic acidN,N-bis(2'-hydroxybenzyl)-3-aminosalicylic acid5-amino-(N,N'-bis-2-hydroxybenzyl)salicylic acid2-hydroxy-5-[bis(2-hydroxybenzyl)amino]benzoic acidBenzoic acid, 5-[bis[(2-hydroxyphenyl)methyl]amino]-2-hydroxy-UNII-7T53EGQ52ZUNII7T53EGQ52ZUNII 7T53EGQ52Z