Drug intelligence / Profile preview

lawsonia inermis extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

**Lawsonia inermis extract** is derived from the leaves of *Lawsonia inermis* L., commonly known as henna. The extract contains a wide spectrum of bioactive phytochemicals including polyphenols (such as gallic acid, catechin, chlorogenic acid, ellagic acid), flavonoids (e.g., quercetin, apigenin, luteolin), coumarins, naphthoquinones (notably lawsone—2-hydroxy-1,4-naphthoquinone), terpenoids (e.g., ursolic acid, betulinic acid), alkaloids, and tannins[1][2][3]. The mechanism of action for *Lawsonia inermis* extract is believed to involve antioxidative activity (scavenging free radicals via polyphenols and flavonoids), antimicrobial (antibacterial and antifungal) effects likely due to naphthoquinones and phenolic compounds, anti-inflammatory and analgesic effects via flavonoids and lawsone, cytotoxic activity against several cancer cell lines (possibly via induction of apoptosis and anti-proliferative effects), and wound healing properties. The extract demonstrates antibacterial effects against both Gram-positive and Gram-negative bacteria, antifungal activity against multiple fungal strains, anti-inflammatory effects, diuretic activity, as well as moderate direct cytotoxicity against breast, colon, and lung cancer cells in vitro[1][2][3]. It is traditionally used for skin, hair, wound therapy, and various health conditions (ulcers, scabies, jaundice, infections, pain, inflammation)[2][3].

Other names
henna extractextracts of lawsonia inermislawsonia inermis leaf extract
02

Targets

PGN (Peptidoglycan)

Beyond the preview

Go deeper on lawsonia inermis extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on lawsonia inermis extract.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call